刘云

姓 名

刘云

性 别

通讯地址

贵州省遵义市新蒲新区学府西路6号

邮 编

563003

邮 箱

liuyunzy@126.com

职 称

教授

职 务

法医学院副院长(主持工作)

简 介

博士、博士生导师。曾任best365英国体育在线(生命科学研究院)副院长,现任best365英国体育在线法医学院副院长(主持工作),贵州省高校科技拔尖人才,贵州省高层次创新型人才(千层次),中国药理学会抗炎免疫药理专业委员会青年委员会委员,贵州省药学会药学青年专业委员会副主任委员,国家自然科学基金同行评议专家。主要从事活性分子抗衰老、抗肿瘤、增强天然免疫的基础与应用转化方面的研究工作,先后主持国家自然科学基金、贵州省科技支撑计划等各级课题10余项。近5年,以第一作者或通讯作者(含共同)在Aging Cell,Nanoscale Horizons,iScience,Virulence等杂志上发表SCI收录论文20余篇;并被同行广泛引用(包括被发表于Chem Soc Rev , Nat Immunol , Natl Sci Rev等高水平杂志的论文所引用),现为Aging Cell, Transl Res, Aging Dis , OncoImmunology等多本国际专业期刊的审稿人。

教育背景

重庆大学生物医学工程博士

学术组织任职

1.贵州省药学会药学青年专业委员会副主任委员

2.中国药理学会抗炎免疫药理专业委员会青年委员会委员

主讲课程

《生物化学》《科技论文绘图技术》

科研项目

1.国家自然科学基金1项,2017.01-2020.12,结题,主持

2.国家自然科学基金1项,2022.01-2025.12,在研,主持

发表论文

部分代表性论文如下:

1.Yi Xiao#*, Fang Liu#, Xinting Zhu#, Sanhua Li#, Lingjie Meng, Nian Jiang, Changyan Yu, Haijuan Wang, Ying Qin, Jing Hui, Chunbo Yu,Yun Liu*. Dioscin integrates regulation of Monosaturated fatty acid metabolism to extend lifespan through XBP-1/SBP-1 dependent manner.iScience , 2023,26: 106265

2.Yi Xiao#,*, Li Zhang#,Yun Liu*. Protocol for assessing the healthspan of Caenorhabditis elegans after potential anti-aging drug treatment.STAR protocols, 2023, 4(2): 102285

3.Yi Xiao#, Li Zhang#, Xinting Zhu, Ying Qin, Changyan Yu, Nian Jiang,Sanhua Li, Fang Liu*,Yun Liu*.Luteolin promotes pathogen resistance inCaenorhabditis elegans via DAF-2/DAF-16 insulin-like signaling pathway.International Immunopharmacology, 2023, 115: 109679

4. Fang Liu#, Haijuan Wang#, Xinting Zhu#,Nian Jiang, Feng Pan, Changwei Song, Chunbo Yu, Changyan Yu,Ying Qin, Jing Hui, Sanhua Li, Yi Xiao*,Yun Liu*. Sanguinarine promotes healthspan and innate immunity through a conserved mechanism of ROS-mediated PMK-1/SKN-1 activation,iScience,2022, 25(3): 103874

5. Yi Xiao#, Fang Liu#, Qinghong Kong, Xinting Zhu, Haijuan Wang, Sanhua Li, Nian Jiang, Changyan Yu, Yun Liu*. Metformin induces S-adenosylmethionine restriction to extend theCaenorhabditis elegans healthspan through H3K4me3 modifiers.Aging Cell, 2022: e13567

6. Yi Xiao#, Huiling Zhang#, Yi Sheng#, Fang Liu, Jiajun Gao, Guosheng Liu, Sanhua Li, Nian Jiang, Changyan Yu, Yun Liu*. Usnic Acid extends healthspan and improves the neurodegeneration diseases via mTOR/PHA-4 signaling pathway inCaenorhabditis elegans.iScience, 2022, 25(12):105539

7. Xinting Zhu#,Fang Liu#, Qinyi Wu#, Sanhua Li, Guoyong Ruan, JianboYang, Changyan Yu, Nian Jiang, Yi Xiao*, Yun Liu*. Brevilin A enhances innate immunity and the resistance of oxidative stress inCaenorhabditis elegans via p38 MAPK pathway. International Immunopharmacology , 2022,113: 109385

8. Wei Yu, Xiao Zhang, Wei Zhang, Minggang Xiong, Yuhan Lin, Ming Chang, Lin Xu, Yi Lu*,Liu Yun* , Jian Zhang*. 19-Hydroxybufalin inhibits non-small cell lung cancer cell proliferation and promotes cell apoptosis via the Wnt/β-catenin pathway.Experimental hematology & oncology, 2021, 10(1): 1-14

9. Fang Liu#, Xinting Zhu#, Yi Li , Chen-jing Wang , Jia-li Fu , Jing Hui, Yi Xiao, Liu Liu, Rong Yan, Xiao-Fei Li*,Liu Yun*. Magnesium demethylcantharidate inhibits hepatocellular carcinoma cell invasion and metastasis via activation transcription factor FOXO1.European Journal of Pharmacology, 2021, 911: 174558

10. Jinghua Li#,Yun Liu#, Xiaonan Li, Gaofeng Liang, Changshun Ruan*, Kaiyong Cai*,ROS self-generation and hypoxia self-enhanced biodegradable magneticnanotheranostics for targeted tumor therapy.Nanoscale Horizons, 2020,5(2): 350-358

11. Yi Xiao#, Qiang Gong#, Wenhong Wang#, Fang Liu, Qinghong Kong, Feng Pan, Xiaoke Zhang, Changyan Yu, Shanshan Hu, Fang Fan, Sanhua Li*,Liu Yun*. The combination of Biochanin A and SB590885 potentiates the inhibition of tumour progression in hepatocellular carcinoma.Cancer Cell International, 2020,20(1):371

12. Yi Xiao#, Fang Liu#, Sanhua Li, Nian Jiang, Changyan Yu, Xinting Zhu, Ying Qin, Jing Hui, Lingjie Meng, Changwei Song, Xiaofei Li*, Liu Yun*. Metformin promotes innate immunity through a conserved PMK-1/p38 MAPK pathway.Virulence, 2020, 11(1): 39-48

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